The State Museum of Pennsylvania is a non-profit history museum at 300 North Street in downtown Harrisburg, Pennsylvania, United States. It is run by the Pennsylvania Historical and Museum Commission to preserve and interpret the Commonwealth's history and culture. It is a part of the Pennsylvania State Capitol Complex.

The museum's central hall features a large statue of William Penn, who founded the Province of Pennsylvania in 1681 during the British colonial era.

The museum includes a multi-media planetarium, as well as four floors of exhibits and displays covering Pennsylvania history from prehistoric times through current events. Visitation averages 315,000 people annually. Among the features are an extensive collection of artifacts and exhibitions related to the American Civil War including Peter Rothermel's massive Battle of Gettysburg: Pickett's Charge, and an extensive collection of industrial and technological innovations, including artwork, paintings, dioramas, and other audio-visuals aid in the interpretation.

There are over three million objects in the museum's collections. The museum has many exhibits that showcase Pennsylvania history. The state museum divided its exhibits into three categories; permanent, changing, and online.